International Journal of Pharmacy and Chemistry

Volume 2, Issue 2, November 2016

  • Comparative Study of Phytochemical and Nutrient Contents of Various Parts of Irvingia gabonensis (Aubry-Lecomte ex O’ Rorke) Baill. and Irvingia wombolu Vermoesen

    Chinelo Anthonia Ezeabara, Ezeani Darlington Somtochukwu

    Issue: Volume 2, Issue 2, November 2016
    Pages: 10-14
    Received: Aug. 17, 2016
    Accepted: Sep. 08, 2016
    Published: Oct. 11, 2016
    DOI: 10.11648/j.ijpc.20160202.11
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    Abstract: The phytochemical and nutrient constituents of seed, leaf, stem bark and root bark of Irvingia gabonensis (Aubry-Lecomte ex O’Rorke) Baill. and I. wombolu Vermoesen were determined and compared with a view to providing additional taxonomic characters for differentiating between the two species, and to supply useful information that would lead to in... Show More
  • Synthesis, Spectral Characterization, Theoretical Evaluation of New Cu(II) and Ni(II) Complexes of Flavon

    Omar H. Al-Obaidi

    Issue: Volume 2, Issue 2, November 2016
    Pages: 15-19
    Received: Sep. 17, 2016
    Accepted: Oct. 12, 2016
    Published: Oct. 21, 2016
    DOI: 10.11648/j.ijpc.20160202.12
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    Abstract: A new series of Cu(II) and Ni(II) complexes with the Flavone ligand were prepared and spectroscopic method and elemental analysis verified their structures. All the prepared complexes have been identified by available spectroscopic tools (UV-Visible and IR) in addition the structure of complexes was characterized by magnetic moments and molar condu... Show More
  • Insecticidal Activity of Essential oil of Parquetina nigrescens (Afzel) Bullock

    Adesola Adebajo Osunsami, Sunkanmi Emmanuel Sotubo, Oladipupo Adejumobi Lawal, Isiaka Ajani Ogunwande, Olanrewaju Ishola Eresanya

    Issue: Volume 2, Issue 2, November 2016
    Pages: 20-23
    Received: Aug. 22, 2016
    Accepted: Sep. 23, 2016
    Published: Oct. 28, 2016
    DOI: 10.11648/j.ijpc.20160202.13
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    Abstract: The essential oil obtained by hydrodistillation of the leaf of Parquetina nigrescens (Afzel) Bullock (Asclepiadaceae) was studied for the insecticidal activity using a conventional procedure. Different concentrations (50, 100, 150, 200 and 250 mg/mL) of P. nigrescens essential oil prepared separately and diluted in DMSO were tested on the maize wee... Show More
  • Identification of Leads as Topoisomerase-II Inhibitors Using Pharmacophore Mapping

    Deveeka Zamare, Shraddha Choudhary, Bishwambhar Mishra

    Issue: Volume 2, Issue 2, November 2016
    Pages: 24-30
    Received: Aug. 27, 2016
    Accepted: Oct. 12, 2016
    Published: Oct. 28, 2016
    DOI: 10.11648/j.ijpc.20160202.14
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    Abstract: DNA topoisomerases are unique enzymes which play a major role in solving the topological problems associated with DNA molecule. Topoisomerase enzymes are highly expressed in cells which undergo rapid and uncontrolled cell divisions. Inhibition of this enzyme represents a major potential therapeutic approach for cancer. The computational tools that ... Show More
  • Autofluorescence of Plant Secretory Cells as Possible Tool for Pharmacy

    Victoria V. Roshchina, Andrei V. Kuchin, Valerii A. Yashin

    Issue: Volume 2, Issue 2, November 2016
    Pages: 31-38
    Received: Sep. 22, 2016
    Accepted: Oct. 12, 2016
    Published: Nov. 03, 2016
    DOI: 10.11648/j.ijpc.20160202.15
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    Abstract: First experiments for identification of intact plant secretory cells filled with products of secondary metabolism known as drugs based on their fluorescence characteristics has been analyzed on some medicinal plants. Autofluorescence of compounds containing in intact and dried cells induced, mainly, by ultra-violet or violet light was well seen in ... Show More
  • Phytochemical Analysis, Antimicrobial and Antioxidant Study of Nigella sativa L

    Sania Feroz, Ghias Uddin

    Issue: Volume 2, Issue 2, November 2016
    Pages: 39-43
    Received: Aug. 30, 2016
    Accepted: Nov. 14, 2016
    Published: Dec. 17, 2016
    DOI: 10.11648/j.ijpc.20160202.16
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    Abstract: The current investigation was designed to assess the preliminary phytochemical analysis, antimicrobial and anti-radical effect of crude methanolic extract and isolated fractions of Nigella sativa seeds using established protocol. The phytochemical analysis revealed the presence of alkaloids, terpenoids, tannins, reducing sugars, saponins, steroids,... Show More
  • Treatment of Textile Waste Effluents Using Moringa Oleifera Lam

    Saminu Falalu

    Issue: Volume 2, Issue 2, November 2016
    Pages: 44-46
    Received: Aug. 28, 2016
    Accepted: Oct. 15, 2016
    Published: Jan. 09, 2017
    DOI: 10.11648/j.ijpc.20160202.17
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    Abstract: Waste effluents samples collected from African textile manufactures ltd (ATM) located in Challawa Kano state, was studied for the effectiveness of using Moring Oleifera lam (Zogale) seed powder in its treatment. The effect of oil extraction (of the seed) and pH – correction of the effluents on the treatment was also studied.It was observed that Mor... Show More
  • Screening Investigation of Novel 1,2,4-Triazole-3-Thione Derivatives on Anticonvulsant Activity

    Dmitryi Pavlovich Kavraiskyi, Sergey Yurievich Shtrygol', Victoria Akopovna Georgiyants, Narzullo Boboevich Saidov

    Issue: Volume 2, Issue 2, November 2016
    Pages: 47-51
    Received: Aug. 30, 2016
    Accepted: Oct. 19, 2016
    Published: Jan. 10, 2017
    DOI: 10.11648/j.ijpc.20160202.18
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    Abstract: 1,2,4-triazole and its derivatives are present in many biologically active aromatic compounds that have different biological properties and clinical applications including anticonvulsant activity. The number of studies in this direction is increasing. Therefore, based on the results of previous computer predictions, 8 novel 1,2,4-triazole-3-thione ... Show More